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The body reacts to stress in a variety of different ways. Some people might experience temporary anxiety, while others might develop phobias or panic attacks. Alcohol and other drugs can trigger physical reactions as well. When someone regularly ingests the same substance, their body develops a tolerance for it. This means that they need more of the substance to feel the effects that they originally experienced. This can lead them to continue consuming the substance even though they know that it is bad for them.