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Schizophrenia is a serious mental illness, and substance use disorders are serious illnesses too. When they show up together, daily life can unravel quickly. Many families wonder whether drugs can “cause” schizophrenia, or if a loved one is using substances to cope with confusing thoughts, voices, or paranoia. The reality is that schizophrenia and substance use influence one another in complex ways. This guide explains what schizophrenia is, how drugs and alcohol affect the illness, what we know about schizophrenia from drug use, and how integrated treatment at Nova Recovery Center can help.