Ketamine and Alcohol: Why Mixing Depressants Can Turn Dangerous Fast
Ketamine is showing up in more places than the club scene. It is still used as an anesthetic, is sometimes prescribed for pain, and in carefully controlled settings it can be part of treatment-resistant depression care. At the same time, alcohol remains one of the most widely used—and misused—substances in the world. Putting the two together may feel common or even casual, but it is anything but safe.
Both ketamine and alcohol act on the central nervous system (CNS). Together they can sharply change breathing, heart function, judgment, and memory in ways that are hard to predict and even harder to reverse once things go wrong. Many people who mix them do not realize how quickly a “good night out” or a “booster” for ketamine therapy can turn into a medical emergency.