Dextromethorphan (DXM) Addiction: Side Effects, Detox, Withdrawal, and Treatment

Close-up of cough syrup being poured from bottle into a metal spoon

Last Updated on September 8, 2025

Dextromethorphan (DXM) is a synthetic substance commonly found in over-the-counter cough and cold medications. While effective at treating symptoms like coughing and congestion when taken as directed, high doses can lead to serious side effects of dextromethorphan, including hallucinations and disassociation. As a result, DXM misuse has become a growing public health concern, especially among teens and young adults.

This medication is available in tablets, capsules, and liquid forms. Taken at recommended doses, it’s safe.

But dextromethorphan abuse—especially with alcohol or other prescription drugs—can be dangerous. High doses can lead to hallucinations, confusion, and serious health risks.

Some users report experiences similar to those produced by dissociative drugs like PCP or ketamine. As a recreational drug, DXM is often misused in social settings where access to illicit drugs is limited.

Many states, including Texas, have banned the sale of DXM to minors due to the increasing number of teens misusing it. As of 2019, 19 U.S. states have restricted access to products like NyQuil and Robitussin. Despite these restrictions, products containing DXM are still widely available, making education and prevention efforts essential.

Common DXM Brand Names

More than 120 products contain DXM. A few well-known examples include:

  • NyQuil
  • Robitussin CoughGels
  • Delsym
  • Children’s Robitussin Cough Long-Acting
  • Sucrets Cough Relief DM
  • Balminil DM
  • Buckleys D

Street Names for DXM

Dex, Robo, Tussin, Red Devils, Poor Man’s Ecstasy, Velvet, and more.

Side Effects of DXM Abuse

The effects of DXM misuse vary depending on the dose and whether other substances are involved. Some people mix DXM with prescription medications, alcohol, or illicit drugs, which can result in severe complications. High doses may cause life-threatening symptoms like respiratory depression, seizures, or coma. Prolonged use can also lead to mental health issues, cognitive decline, and behavioral changes.

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Symptoms of DXM abuse may include:

  • Nausea
  • Sweating
  • Panic attacks
  • Racing heart
  • Confusion
  • Loss of balance
  • Slurred speech
  • Sedation
  • Disassociation

Long-term abuse can result in permanent changes in brain chemistry and behavior. People who mix DXM with alcohol or sedatives are at even greater risk for overdose, high blood pressure, and death.

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Signs of Addiction and Risk Factors

Teens are especially at risk because of how easy it is to get DXM. According to the National Institute on Drug Abuse, about 3% of high school seniors admit to misusing cough medicine. Many teens perceive these medications as “safe” due to their legal status, not realizing the serious risks involved.

Warning signs of DXM addiction include:

  • Buying large amounts of cough medicine
  • Pulling away from friends and family members
  • Needing higher doses to feel effects
  • Feeling sick when not using
  • Wanting to quit but being unable

Several higher risk factors increase the likelihood of DXM misuse, especially among young people. These include peer pressure, lack of supervision, and easy access to medications. Untreated mental health disorders such as anxiety or depression can also drive individuals to self-medicate. Additionally, environmental factors like community norms around drug use or exposure to drug addiction at home may further increase the risk.

Detox and Withdrawal from DXM

Long-term recovery begins with detox. Withdrawal symptoms can include:

  • Anxiety
  • Depression
  • Trouble sleeping
  • Diarrhea
  • Sweating
  • Shaking
  • Hallucinations

These symptoms can begin within hours of stopping use and may last several days. Cravings and mood swings often make quitting difficult without medical help. Medical detox helps people quit safely. Health care professionals monitor symptoms and offer support. A personalized treatment plan makes the process easier and safer. Professionals may also prescribe medications to reduce discomfort during detox.

During medical detox, a trained care team provides around-the-clock supervision and support. This type of care is especially important for those experiencing severe withdrawal from DXM, GHB, or other substances. Detox alone is not a cure, but it is the first essential step in the recovery process and long-term addiction treatment.

Treatment for DXM Addiction

An effective treatment plan includes a wide range of therapies tailored to each person’s needs. This often involves individual and group therapy sessions, where clients explore past trauma, build coping skills, and learn relapse prevention strategies. Many treatment centers also address mental health conditions like depression or PTSD that frequently co-occur with substance use disorders.

The most effective treatment options include:

  • Cognitive Behavioral Therapy (CBT)
  • Educational sessions
  • 12-Step or similar programs
  • Support groups
  • Life coaching

Therapists work with clients to identify triggers, process emotional trauma, and build healthier coping strategies. Group sessions help individuals find connection and accountability, while family therapy can repair relationships and strengthen support systems at home.

According to the National Institute on Drug Abuse, addiction treatment should last at least 12 months to support sustained recovery.

Inpatient vs. Outpatient Rehab

Inpatient Rehab

  • Stay at the rehab center full-time
  • Follow a daily routine
  • Attend group and individual therapy
  • Engage in structured recovery activities
  • Remove distractions and access to substances

Outpatient Rehab

  • Live at home or in a sober living program
  • Attend sessions on a set schedule
  • Keep work or school responsibilities
  • Practice new coping skills in real-life settings
  • Maintain independence with accountability

The right level of care depends on the severity of addiction, mental health conditions, and home environment. Inpatient rehab may be better for those with co-occurring disorders, while outpatient care offers more flexibility.

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Sober Living and Aftercare Support

Sober living programs offer residents the opportunity to rebuild their lives in a supportive, substance-free environment. These homes encourage independence while discouraging harmful behaviors such as drinking alcohol or using drugs. With structure, peer support, and personal accountability, sober living greatly improves one’s long-term recovery outcomes and quality of life.

Aftercare programs give ongoing support through weekly group meetings. They help people stay on track and avoid relapse with the help of healthcare professionals. Clients can continue to explore relapse prevention strategies, build relationships with others in recovery, and receive support during challenging life transitions. Some facilities also offer alumni programs, recovery coaching, and online support groups.

Cost of Treatment and Getting Help

The cost of DXM addiction treatment depends on the level of care needed. Options include:

  • Health insurance
  • HSA accounts
  • Credit plans
  • Employee Assistance Programs (EAP)
  • Sliding scale fees for qualified individuals
  • Payment plans or scholarships at some facilities

Many insurance providers cover detox, inpatient drug rehab, and aftercare services, but coverage details vary. It’s important to verify benefits and ask about payment options early in the admissions process. Most outpatient drug rehab treatment centers have financial counselors available to help you navigate the insurance process and find a solution that fits your budget.

Take the First Step

If you or someone you love is struggling with DXM abuse, help is available. Call (512) 605-2955 to speak with a recovery specialist today. Recovery is possible, and taking the first step can lead to a healthier, more fulfilling life.

FAQs About DXM Abuse and Risks

No, DXM (dextromethorphan) is not an opioid. It is a cough suppressant found in many over-the-counter cold and cough medicines. However, at high doses, it can act as a dissociative drug, leading to dangerous side effects and a high potential for abuse.

DXM is classified as a synthetic cough suppressant. In low doses, it safely reduces coughing, but when misused in large amounts, it produces psychoactive effects such as hallucinations, euphoria, and dissociation.

Dextromethorphan is generally considered low-risk when used occasionally at recommended doses during pregnancy, but it should only be taken under medical supervision. Misuse or high doses of DXM can pose serious risks to both the mother and baby.

DXM remains legal because it is effective for cough suppression when taken as directed. However, due to increasing misuse, some states have placed restrictions on sales, especially to minors.

DXM affects the brain’s NMDA receptors, and in higher doses, it can cause dizziness, confusion, blurred vision, and even hallucinations. These effects are signs of misuse and can be dangerous.

DXM is chemically similar to dissociative drugs like ketamine and PCP, though much weaker. At high doses, it produces comparable mind-altering effects, which is why it is often misused.

Taking too much DXM can cause overdose symptoms, including rapid heartbeat, vomiting, seizures, brain damage, or even death. Combining DXM with alcohol or other drugs increases these risks.

Abusing cough syrup with DXM is often called “robotripping” or “skittling.” These slang terms refer to consuming large amounts to achieve a high, which is extremely unsafe.

In slang, cough syrup abuse may be referred to as “lean,” “sizzurp,” or “purple drank,” especially when combined with soda or candy. This dangerous trend glamorizes misuse but can lead to addiction and overdose.

Some prescription cough syrups contain codeine, an opioid narcotic, which carries a high risk of addiction. While DXM itself is not an opioid, it is the most common active ingredient in non-prescription cough medicines that can be misused.

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