Close-up of prescription pills, a syringe, and a spoon representing drug misuse and the risks of improper medication use.

Drug Misuse: Definition, Examples, and Help

Key Takeaways

  • Drug misuse means using a substance in a way that goes against medical or legal guidance, such as taking more than prescribed or using someone else’s medication.

  • Substance misuse is a broader term that includes alcohol, tobacco, prescription drugs, and illegal substances used improperly.

  • The term “abuse” is being replaced in clinical settings with “substance use disorder”, which focuses on compulsive patterns of use rather than moral judgment.

  • Common examples of misuse include doubling doses, mixing medications with alcohol, or using prescriptions to get high.

  • Misuse raises the risk of overdose, dependence, and addiction, especially when opioids, sedatives, or stimulants are involved.

  • Prevention strategies include following medical instructions, safe storage, avoiding mixing drugs with alcohol, and proper disposal of unused medications.

  • If misuse becomes hard to control or causes harm, help is available. Contact a doctor, pharmacist, or resources like the SAMHSA Helpline (1-800-662-HELP) for support.

Table of Contents

Drug misuse sits at the crossroads of addiction and mental health, and the words used to describe it matter. Many people hear “abuse” and “misuse” used as if they mean the same thing; they do not always, and the distinction influences care decisions, insurance coverage, and how people see themselves. This guide explains what the terms mean, how they are used by health agencies, and what real‑world behavior counts as misuse, along with practical steps for support.

What is drug misuse?

In public health, misuse means using a drug in a way that is not consistent with medical or legal guidance, including taking more than directed, taking it more often, using a medicine for a different reason than prescribed, or using a drug without a prescription. Misuse may involve illegal drugs, but it also includes alcohol, nicotine, and common medicines bought over the counter, all of which can cause harm when used improperly.

Substance misuse definition

Substance misuse is a broader term. It covers the risky or inappropriate use of any mood‑altering substance, whether legal or illegal—alcohol, tobacco, cannabis, prescription opioids, benzodiazepines, stimulants, cough syrups, and inhalants all fall in this group. Health groups use “substance misuse” because it is clear and less stigmatizing than older labels, and because it captures both occasional misuse and patterns that may, over time, meet criteria for a medical diagnosis.

Drug abuse vs. misuse: what is the difference?

Many clinicians now avoid the word “abuse.” Preferred wording is “misuse” for prescription medicines used other than as directed, and “use” for illegal drugs. When drug use becomes compulsive despite harm, clinicians diagnose a substance use disorder (SUD) rather than “abuse.” Abuse still appears in older articles and some laws, but in day‑to‑day care the focus is whether use is safe, risky, or meets SUD criteria, which are defined by diagnostic checklists rather than moral judgment.

Quick contrast

  • Misuse: Using a medication in a way other than prescribed; using someone else’s prescription; or using any drug to “get high.” 

  • Use disorder: Ongoing, compulsive use with clear harm or loss of control. The behavior continues despite problems at school, work, home, or with health, and severity can be classified as mild, moderate, or severe.

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Which of these is an example of drug misuse?

Misuse shows up in everyday choices. Common examples include:

  • Taking two pain pills when the label says one, or taking doses closer together than directed. 

  • Using a friend’s opioid after a dental procedure because it “still hurts.” 

  • Mixing a sedative, like a benzodiazepine, with alcohol to sleep. 

  • Crushing and snorting a pill that was meant to be swallowed. 

  • Taking a stimulant prescribed to someone else “to study.” 

  • Using cough medicine or cold remedies to get high. 

  • Keeping and using leftover antibiotics for a later illness (still misuse even if intent is relief).

Each of these uses a substance for a purpose or in a dose that does not match medical or legal guidance; even a single episode can cause serious harm.

Why does misuse happen?

Reasons vary. Someone may be in pain, anxious, or unable to sleep. A person may want to work longer hours or escape stress. Social pressure, easy access, and not understanding risk all play a role. Past trauma, depression, ADHD, and other mental health conditions can raise risk; so can a family history of addiction. None of these causes misuse by itself, but together they can make risky choices more likely; targeted prevention and access to evidence‑based care can reduce these risks.

Health risks and harms

  • Overdose and poisoning. Prescription opioids, CNS depressants (e.g., benzodiazepines), and stimulants are the classes most often misused. High doses or dangerous mixes can slow breathing, raise blood pressure, or trigger seizures. 

  • Tolerance and dependence. Over time the body adapts. Stopping leads to withdrawal, and a person may take more to feel the same effect. This physiological dependence can develop even when a drug was started for a legitimate medical need. 

  • Addiction (substance use disorder). For some, use becomes compulsive and continues despite harm; the condition involves persistent brain‑circuit changes affecting reward, stress response, and self‑control. 

  • Interactions. Alcohol, benzodiazepines, and opioids together greatly raise overdose risk. The combination can suppress breathing, impair coordination, and heighten sedation to a dangerous degree. Many cold or allergy medicines also interact with prescribed drugs. 

  • Injury and legal problems. Slowed reaction times, impaired judgment, and driving under the influence raise the risk of accidents and arrests.

Red flags to watch for

  • Taking higher or more frequent doses than planned

  • Borrowing prescriptions or guarding your own pills

  • Cravings, irritability, or trouble sleeping between doses

  • Missing work, school, or family plans because of substance use

  • Mixing medications with alcohol or other drugs

  • Needing the drug to feel “normal”

If you see several of these signs together, it is time to talk with a clinician.

Prevention and safer use

  • Follow the label and your prescriber’s plan. Ask what to do if pain or symptoms break through. 

  • Use one pharmacy and keep an updated list of your medicines. Bring that list to every visit so clinicians can reconcile doses and spot interactions. 

  • Store medicines safely. Lock them away and never share them. 

  • Avoid mixing with alcohol or other sedatives unless a doctor says it is safe. 

  • Dispose of leftovers. Use local take‑back programs or pharmacist‑guided disposal steps.

  • Ask about non‑drug options. Physical therapy, sleep therapy, and counseling often help. 

  • Carry naloxone if you or someone in your home uses opioids.

Getting help

If you are worried about your use, you are not alone and help works. Start with your primary care clinician, pharmacist, or a local health clinic, each of whom can screen for risk, explain options, and refer you to specialty care when needed. If opioids, sedatives, or multiple substances are involved, consider medical detox in Austin to stabilize safely before ongoing treatment.


 Treatment may include counseling, medications (such as buprenorphine or naltrexone for opioid use disorder), peer support, and help with sleep, pain, or mood concerns.

How Nova Recovery Center Supports Lasting Recovery from Drug Misuse

Nova Recovery Center provides comprehensive support for individuals struggling with drug misuse, addiction, and abuse. Our programs are built on evidence-based treatment methods that address both the physical and psychological aspects of substance use. We offer medically supervised detox services to ensure a safe and stable start to recovery, followed by structured residential and outpatient programs that focus on long-term healing. Clients work with experienced counselors and recovery specialists who help identify the root causes of misuse, such as trauma, stress, or co-occurring mental health conditions.

At Nova, treatment plans are individualized, giving each person the tools and strategies they need to build a sustainable life in sobriety. Our approach emphasizes accountability, relapse prevention, and the development of healthy coping skills that can replace harmful behaviors. We also provide access to peer support, life skills training, and family involvement to strengthen long-term outcomes. 

With a focus on both personal growth and community support, Nova Recovery Center equips clients with the resources they need to break the cycle of misuse and create lasting change. By addressing addiction at its core and providing a full continuum of care, we help individuals move from early recovery to long-term sobriety with confidence and stability.

Frequently Asked Questions About Drug Misuse

Drug misuse is using a medication or substance in a way that isn’t consistent with medical or legal guidance—such as taking a higher dose, taking it more often, using someone else’s prescription, or using it to get high.

“Misuse” describes use that isn’t as directed (often for prescription medicines). “Abuse” is being replaced in clinical practice by the diagnosis substance use disorder (SUD), which refers to a pattern of compulsive use that continues despite harm.

Substance misuse is a public‑health term that includes the risky or inappropriate use of any mood‑altering substance—alcohol, tobacco, illegal drugs, and medications.

Examples include taking a friend’s pain pills, doubling your dose to “catch up,” crushing and snorting tablets meant to be swallowed, or mixing a sedative with alcohol to sleep.

NIDA identifies three classes most often misused: opioids, central nervous system (CNS) depressants (e.g., benzodiazepines), and stimulants.

Yes. Misuse can progress to substance use disorder, a treatable medical condition.

No. Misuse is about how a drug is used (e.g., not as directed). Addiction/SUD is a diagnosis marked by loss of control, cravings, and continued use despite harm.

Red flags include taking larger or more frequent doses, borrowing prescriptions, cravings, withdrawal symptoms, and problems at work, school, or home.

Yes. Combining opioids with other CNS depressants (like benzodiazepines or alcohol) greatly increases overdose risk and should be avoided unless specifically directed by a clinician.

Follow your prescriber’s directions, discuss interactions with a clinician or pharmacist, use one pharmacy when possible, and never share medicines. Dispose of leftovers through take‑back programs or FDA‑recommended methods.

Use DEA‑authorized take‑back options or FDA‑approved mail‑back/drop‑off sites; if unavailable, follow FDA home‑disposal guidance (or the Flush List for select high‑risk medicines).

Call SAMHSA’s National Helpline (1‑800‑662‑HELP) for free, confidential treatment referral. If you’re in emotional distress or crisis, call/text 988 for the Suicide & Crisis Lifeline.

Medical Disclaimer

The information on this page is intended for educational purposes only and should not replace professional medical advice, diagnosis, or treatment. Prescription and over-the-counter medications should always be used only as directed and under the guidance of a licensed healthcare provider. Do not begin, discontinue, or change the way you take any medication without first consulting your doctor or pharmacist. If you are experiencing severe side effects, withdrawal symptoms, or a medical emergency, call 911 in the United States or seek immediate medical help. For free and confidential support with mental health or substance use concerns, you can dial 988 to connect with the Suicide & Crisis Lifeline, available 24/7.

Nova Recovery Center Editorial Guidelines

By instituting a policy, we create a standardized approach to how we create, verify, and distribute all content and resources we produce. An editorial policy helps us ensure that any material our writing and clinical team create, both online and in print, meets or exceeds our standards of integrity and accuracy. Our goal is to demonstrate our commitment to education and patient support by creating valuable resources within our realm of expertise, verifying them for accuracy, and providing relevant, respectful, and insightful data to our clients and families.

  1. National Institute on Drug Abuse. (2023, March 6). Misuse of prescription drugs: Research report—Overview. National Institute on Drug Abuse (NIDA). Retrieved October 4, 2025, from
    https://nida.nih.gov/publications/research-reports/misuse-prescription-drugs/overview
  2. Mayo Clinic Staff. (2022, October 25). Prescription drug abuse: Symptoms and causes. Mayo Clinic. Retrieved October 4, 2025, from
    https://www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/symptoms-causes/syc-20376813
  3. MedlinePlus. (2025, May 30). Prescription drug misuse. U.S. National Library of Medicine. Retrieved October 4, 2025, from
    https://medlineplus.gov/prescriptiondrugmisuse.html
  4. American Psychiatric Association. (2024, April). What is a substance use disorder? American Psychiatric Association. Retrieved October 4, 2025, from
    https://www.psychiatry.org/patients-families/addiction-substance-use-disorders/what-is-a-substance-use-disorder
  5. Substance Abuse and Mental Health Services Administration. (2024, October 24). Helplines. SAMHSA. Retrieved October 4, 2025, from
    https://www.samhsa.gov/find-help/helplines
  6. U.S. Food and Drug Administration. (2025, April 16). Where and how to dispose of unused medicines. FDA. Retrieved October 4, 2025, from
    https://www.fda.gov/consumers/consumer-updates/where-and-how-dispose-unused-medicines
  7. Dowell, D., Ragan, K. R., Jones, C. M., Baldwin, G. T., & Chou, R. (2022, November 4). CDC clinical practice guideline for prescribing opioids for pain—United States, 2022. MMWR Recommendations and Reports, 71(3), 1–95. Centers for Disease Control and Prevention. Retrieved October 4, 2025, from
    https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm.

Mat Gorman

Medical Content Strategist

Mat Gorman is a board-certified mental health writer and medical researcher with over a decade of experience in addiction recovery education. He specializes in translating complex clinical topics into clear, compassionate content that empowers families and individuals seeking treatment. Mat has collaborated with recovery centers, licensed therapists, and physicians to publish evidence-based resources across the behavioral health space. His passion for helping others began after witnessing the struggles of loved ones facing substance use disorder. He now uses his platform to promote hope, clarity, and long-term healing through accurate, stigma-free information.
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